D, weak D (Du), and partial D: the molecular story unfolds
نویسندگان
چکیده
منابع مشابه
Evidence of genetic diversity underlying Rh D-, weak D (Du), and partial D phenotypes as determined by multiplex polymerase chain reaction analysis of the RHD gene.
The human blood group Rh antigens are expressed by proteins encoded by a pair of highly homologous genes located at chromosome 1p34-36. One of the genes (RHCE) encodes Rh CcEe antigens, while the other (RHD) the D antigen. Point mutations in the RHCE gene generate the C/c and E/e polymorphisms, while it has been shown that an RHD gene deletion can generate the D-negative phenotype. We have anal...
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ژورنال
عنوان ژورنال: Transfusion
سال: 1996
ISSN: 0041-1132,1537-2995
DOI: 10.1046/j.1537-2995.1996.36296181917.x